Behavioural factors associated with cutaneous anthrax in Musadzi area of Gokwe North, Zimbabwe

A research article on behavioural factors that determine how some residents in Musadzi area,Zimbabwe contract human cutaneous anthrax.Anthrax is a bacterial disease caused by Bacillus anthracis. It is primarily a disease of herbivores, although few, if any, warm-blooded species are entirely immune to it. From earliest historical records until the development of an effective veterinary vaccine midway through the 20th century, anthrax was one of the foremost causes of uncontrolled mortality in domestic animals worldwide. Humans contract anthrax directly from animals or through animal products. The disease is still enzootic in most countries of Africa and Asia, a number of European countries, and countries/areas of the American continent and certain areas of Australia. It still occurs sporadically in many other countries

Treatment outcomes of patients on anti-retrovirals after six months of treatment, Khami Clinic, Bulawayo, Zimbabwe

A CAJM review of HIV/AIDS treatment of infected patients on medication after 6 months of administering anti-retrovirals.It was in 1985 that the first case of HIV tested positive in Zimbabwe. The AIDS epidemic has grown since then to become one of the most serious public health challenges to ever face the nation. According to the 2003 HIV estimates, 24,6% of adults aged 15 to 49 years were infected. Whilst they cannot cure HIV/AIDS, treatment of HIV with Highly Active Antiretroviral Therapy (HAART) can transform the natural course of HIV infection by reducing morbidity and mortality as has been observed in many industrialized countries. It is recommended for patients with symptomatic AIDS, WHO Adult Stage IV and advanced Stage III irrespective of the CD4 cell count or total lymphocyte count

Range-space variants and inexact matrix-vector products in Krylov solvers for linear systems arising from inverse problems

International audienceThe objects of this paper are to introduce range-space variants of standard Krylov iterative solvers for unsymmetric and symmetric linear systems and to discuss how inexact matrix-vector products may be used in this context. The new range-space variants are characterized by possibly much lower storage and computational costs than their full-space counterparts, which is crucial in data assimilation applications and other inverse problems. However, this gain is achieved without sacrificing the inherent monotonicity properties of the original algorithms, which are of paramount importance in data assimilation applications. The use of inexact matrix-vector products is shown to further reduce computational cost in a controlled manner. Formal error bounds are derived on the size of the residuals obtained under two different accuracy models, and it is shown why a model controlling forward error on the product result is often preferable to one controlling backward error on the operator. Simple numerical examples finally illustrate the developed concepts and methods

A New Preconditioning Approachfor an Interior Point–Proximal Method of Multipliers for Linear and Convex Quadratic Programming

In this paper, we address the efficient numerical solution of linear and quadratic programming problems, often of large scale. With this aim, we devise an infeasible interior point method, blended with the proximal method of multipliers, which in turn results in a primal-dual regularized interior point method. Application of this method gives rise to a sequence of increasingly ill-conditioned linear systems which cannot always be solved by factorization methods, due to memory and CPU time restrictions. We propose a novel preconditioning strategy which is based on a suitable sparsification of the normal equations matrix in the linear case, and also constitutes the foundation of a block-diagonal preconditioner to accelerate MINRES for linear systems arising from the solution of general quadratic programming problems. Numerical results for a range of test problems demonstrate the robustness of the proposed preconditioning strategy, together with its ability to solve linear systems of very large dimension

Field Epidemiology and Laboratory Training Programs in sub-Saharan Africa from 2004 to 2010: need, the process, and prospects

As of 2010 sub-Saharan Africa had approximately 865 million inhabitants living with numerous public health challenges. Several public health initiatives [e.g., the United States (US) President’s Emergency Plan for AIDS Relief and the US President’s Malaria Initiative] have been very successful at reducing mortality from priority diseases. A competently trained public health workforce that can operate multi-disease surveillance and response systems is necessary to build upon and sustain these successes and to address other public health problems. Sub-Saharan Africa appears to have weathered the recent global economic downturn remarkably well and its increasing middle class may soon demand stronger public health systems to protect communities. The Epidemic Intelligence Service (EIS) program of the US Centers for Disease Control and Prevention (CDC) has been the backbone of public health surveillance and response in the US during its 60 years of existence. EIS has been adapted internationally to create the Field Epidemiology Training Program (FETP) in several countries. In the 1990s CDC and the Rockefeller Foundation collaborated with the Uganda and Zimbabwe ministries of health and local universities to create 2-year Public Health Schools Without Walls (PHSWOWs) which were based on the FETP model. In 2004 the FETP model was further adapted to create the Field Epidemiology and Laboratory Training Program (FELTP) in Kenya to conduct joint competencybased training for field epidemiologists and public health laboratory scientists providing a master’s degree to participants upon completion. The FELTP model has been implemented in several additional countries in sub-Saharan Africa. By the end of 2010 these 10 FELTPs and two PHSWOWs covered 613 million of the 865 million people in sub-Saharan Africa and had enrolled 743 public health professionals. We describe the process that we used to develop 10 FELTPs covering 15 countries in sub-Saharan Africa from 2004 to 2010 as a strategy to develop a locally trained public health workforce that can operate multi-disease surveillance and response systems.Key words: Field epidemiology, laboratory management, multi-disease surveillance and response systems, public health workforce capacity buildin

Correction to: Water Resources in Africa under Global Change: Monitoring Surface Waters from Space

International audienc

Within-Gender Changes in HIV Prevalence among Adults between 2005/6 and 2010/11 in Zimbabwe

INTRODUCTION: Zimbabwe has reported significant declines in HIV prevalence between 2005/06 and 2010/11 Demography and Health Surveys; a within-gender analysis to identify the magnitude and factors associated with this change, which can be masked, is critical for targeting interventions. METHODS: We analyzed change in HIV prevalence for 6,947 women and 5,848 men in the 2005/06 survey and 7,313 women and 6,250 men in 2010/11 surveys using 2005/06 as referent. The data was analyzed taking into consideration the survey design and therefore the svy, mean command in Stata was used in both linear and logistic regression. RESULTS: There were similar proportional declines in prevalence at national level for males (15% p=0.011) and females (16%,p=0.008). However, there were variations in decline by provincial setting, demographic variables of age, educational level and some sexual risk behaviours. In logistic regression analysis, statistically significant declines were observed among men in Manicaland, Mashonaland East and Harare (p<0.01) and for women in Manicaland, Mashonaland Central and Harare (p<0.01). Although not statistically significant, numerical increases were observed among men in Matebeleland North, Matebeleland South, Midlands and for both men and women in Bulawayo. Young women in the age range 15-34 experienced a decline in prevalence (p<0.01) while older men 30-44 had a statistically significant decline (p<0.01). Having a secondary and above education, regardless of employment status for both men and women recorded a significant decline. For sexual risk behaviours, currently in union for men and women and not in union for women there was a significant decline in prevalence. CONCLUSION: Zimbabwe has reported a significant decline among both men and women but there are important differentials across provinces, demographic characteristics and sexual risk behaviours that suggest that the epidemic in Zimbabwe is heterogeneous and therefore interventions must be targeted in order to achieve epidemic control

Increasing leadership capacity for HIV/AIDS programmes by strengthening public health epidemiology and management training in Zimbabwe

<p>Abstract</p> <p>Background</p> <p>Increased funding for global human immunodeficiency virus prevention and control in developing countries has created both a challenge and an opportunity for achieving long-term global health goals. This paper describes a programme in Zimbabwe aimed at responding more effectively to the HIV/AIDS epidemic by reinforcing a critical competence-based training institution and producing public health leaders.</p> <p>Methods</p> <p>The programme used new HIV/AIDS programme-specific funds to build on the assets of a local education institution to strengthen and expand the general public health leadership capacity in Zimbabwe, simultaneously ensuring that they were trained in HIV interventions.</p> <p>Results</p> <p>The programme increased both numbers of graduates and retention of faculty. The expanded HIV/AIDS curriculum was associated with a substantial increase in trainee projects related to HIV. The increased number of public health professionals has led to a number of practically trained persons working in public health leadership positions in the ministry, including in HIV/AIDS programmes.</p> <p>Conclusion</p> <p>Investment of a modest proportion of new HIV/AIDS resources in targeted public health leadership training programmes can assist in building capacity to lead and manage national HIV and other public health programmes.</p